Evidence-based recommendation for obstetric problems (IGHGa) b

This page is part of the PanCare follow-up recommendations for surveillance of late effects. Click here, for more information on these recommendations.

Who is at risk for obstetric problems?

Female CAYA cancer survivors treated with

  • radiotherapy to a volume exposing the uterus

What obstetric problems might occur?

  • Miscarriage

  • Premature birth
  • Low birth weight

What surveillance modality should be used and at what frequency should it be performed?

  • High-risk obstetric surveillance d

    during pregnancy

What other advice should be given?

  • HCPs should discuss the risk of adverse obstetric outcomesc based on radiotherapy to a volume exposing the uterus with all female CAYA cancer survivors of reproductive age

What should be done if abnormalities are identified?

  • Refer to the appropriate HCP


While PanCare strives to provide accurate and complete information that is up-to-date as of the date of publication, we acknowledge that the sequence of referral and diagnostic tests might vary according to the local and national healthcare system logistics.

It is recognised that survivors and their healthcare professionals have the final responsibility for making decisions concerning their long-term follow-up care. As such, they may choose to either adopt these recommendations or not to do so after individual informed discussion. It is good practice to document this decision.

In addition to regular surveillance, real-time awareness and prompt reporting of new symptoms and signs is essential to the early detection and timely treatment of late effects.

No warranty or representation, expressed or implied, is made concerning the accuracy, reliability, completeness, relevance, or timeliness of this information.

The PanCare materials are free to use for anyone aiming to inform about late effects and long-term survivorship care. However, no financial advantage may be achieved. All communication should reference PanCare and link to the PanCare website.

a This recommendation reflects the content of the IGHG Counselling and Surveillance of Obstetric Risks guideline. The guideline will be published in a peer-reviewed journal soon.

b Further recommendations regarding cardiomyopathy surveillance before and/or during pregnancy are specified in the Consensus-based recommendation for surveillance of cardiac problems.

c There is no evidence to support that survivors have an increased risk of giving birth to a child with congenital anomalies.

d Recommended due to the risk of premature birth and low birth weight.