PanCare follow-up recommendations for surveillance of late effetcs
- Higher risk groups
- Alopecia
- Cerebrovascular problems
- Dental and oral problems
- Gastro-intestinal problems
- Peripheral neuropathy
- Health promotion
- Subsequent neoplasms
- Subsequent melanoma and non-melanoma skin cancer
- Cancer-related fatigue
- Psychosocial problems
- Mental health problems
- Chronic pain
- Neurocognitive problems
- Eye problems
- Craniofacial growth problems
- Spine scoliosis and kyphosis
- Lower urinary tract problems
- Obstetric problems
- Subsequent thyroid cancer
- Subsequent CNS neoplasms
- Subsequent breast cancer
- Subsequent colorectal cancer
- Impaired glucose metabolism and diabetes mellitus
- Dyslipidaemia
- Overweight and obesity
- Hypertension
- Bone problems
- Hypothalamic-pituitary (HP) axis problems
- Central precocious puberty (CPP)
- Ear problems
- Thyroid function problems
- Cardiac problems
- Coronary artery disease
- Pulmonary problems
- Renal problems
- Liver problems
- Spleen problems
- Male fertility problems and sexual dysfunction
- Premature ovarian insufficiency
NEUROCOGNITIVE PROBLEMS
Consensus-based recommendation for surveillance of neurocognitive problems
This page is part of the PanCare follow-up recommendations for surveillance of late effects. Click here, for more information on these recommendations.
Click here, to read this recommendation in PLAIN language.
Who is at risk for neurocognitive problems?
CAYA cancer survivors treated with or with a history of
- a CNS tumour
- brain surgery
- radiotherapy to a volume exposing the brain, including TBI
- high dose cytarabine IV
- high dose methotrexate IV
- any chemotherapy IT
especially if the survivor was treated at a young age
What neurocognitive problems might occur?
Problems in the following cognitive domains:
- Academic and school performance
- Attention
- Executive functions
- Intelligence
- Language
- Memory
- Processing speed
- Visual-motor integration
What surveillance modality should be used and at what frequency should it be performed?
- A history with specific attention to educational and/or vocational progress or decline
at least every 2 years in survivors ≤ 18 years of age, and at least every 5 years in survivors > 18 years of age
What should be done if abnormalities are identified?
- Refer to a (neuro)psychologist for a formal neuropsychological evaluation
Disclaimer
While PanCare strives to provide accurate and complete information that is up-to-date as of the date of publication, we acknowledge that the sequence of referral and diagnostic tests might vary according to the local and national healthcare system logistics.
It is recognised that survivors and their healthcare professionals have the final responsibility for making decisions concerning their long-term follow-up care. As such, they may choose to either adopt these recommendations or not to do so after individual informed discussion. It is good practice to document this decision.
In addition to regular surveillance, real-time awareness and prompt reporting of new symptoms and signs is essential to the early detection and timely treatment of late effects.
No warranty or representation, expressed or implied, is made concerning the accuracy, reliability, completeness, relevance, or timeliness of this information.
The PanCare materials are free to use for anyone aiming to inform about late effects and long-term survivorship care. However, no financial advantage may be achieved. All communication should reference PanCare and link to the PanCare website.
IV = intravenous, IT = intrathecal